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Design and Evaluation of New pH-Sensitive Amphiphilic Cationic Lipids for siRNA Delivery
Synthetic small interfering RNA (siRNA) has become the basis of a new generation of gene-silencing cancer therapeutics. However, successful implementation of this novel therapy relies on the ability to effectively deliver siRNA into target cells and to prevent degradation of siRNA in lysosomes after...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060977/ https://ncbi.nlm.nih.gov/pubmed/23796431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.06.019 |
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