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Design and Evaluation of New pH-Sensitive Amphiphilic Cationic Lipids for siRNA Delivery

Synthetic small interfering RNA (siRNA) has become the basis of a new generation of gene-silencing cancer therapeutics. However, successful implementation of this novel therapy relies on the ability to effectively deliver siRNA into target cells and to prevent degradation of siRNA in lysosomes after...

詳細記述

保存先:
書誌詳細
主要な著者: Malamas, Anthony S., Gujrati, Maneesh, Kummitha, China M., Xu, Rongzuo, Lu, Zheng-Rong
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060977/
https://ncbi.nlm.nih.gov/pubmed/23796431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.06.019
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