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Design and Evaluation of New pH-Sensitive Amphiphilic Cationic Lipids for siRNA Delivery

Synthetic small interfering RNA (siRNA) has become the basis of a new generation of gene-silencing cancer therapeutics. However, successful implementation of this novel therapy relies on the ability to effectively deliver siRNA into target cells and to prevent degradation of siRNA in lysosomes after...

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Detaylı Bibliyografya
Asıl Yazarlar: Malamas, Anthony S., Gujrati, Maneesh, Kummitha, China M., Xu, Rongzuo, Lu, Zheng-Rong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060977/
https://ncbi.nlm.nih.gov/pubmed/23796431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.06.019
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