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Endosomal escape and siRNA delivery with cationic shell crosslinked knedel-like nanoparticles with tunable buffering capacities

Cationic shell crosslinked knedel-like nanoparticles (cSCKs) have emerged as a highly efficient transfection agent for nucleic acids delivery. In this study, a new class of cSCKs with tunable buffering capacities has been developed by altering the amounts of histamines and primary amines incorporate...

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Detalhes bibliográficos
Main Authors: Shrestha, Ritu, Elsabahy, Mahmoud, Florez-Malaver, Stephanie, Samarajeewa, Sandani, Wooley, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582407/
https://ncbi.nlm.nih.gov/pubmed/22901966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.07.054
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