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Degradability of Poly(lactic acid)-containing Nanoparticles: Enzymatic access through a crosslinked shell barrier
Comparative studies of bulk samples of hydrolytically-degradable poly(lactic acid) (PLA) vs. core-shell block copolymer micelles having PLA cores revealed remarkable acceleration in the proteinase K enzymatic hydrolysis of the nanoparticulate forms, and demonstrated that even with amidation-based sh...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265020/ https://ncbi.nlm.nih.gov/pubmed/22257265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2095602 |
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