Synthesis and In Vivo Pharmacokinetic Evaluation of Degradable Shell Crosslinked Polymer Nanoparticles with Poly(carboxybetaine) vs. Poly(ethylene glycol) Surface-grafted Coatings

Nanoparticles with tunable pharmacokinetics are desirable for various biomedical applications. Poly(ethylene glycol) (PEG) is well known to create “stealth” effects to stabilize and extend the blood circulation of nanoparticles. In this work, poly(carboxybetaine) (PCB), a new non-fouling polymer mat...

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Detalhes bibliográficos
Main Authors: Li, Ang, Luehmann, Hannah P., Sun, Guorong, Samarajeewa, Sandani, Zou, Jiong, Zhang, Shiyi, Zhang, Fuwu, Welch, Michael J., Liu, Yongjian, Wooley, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485677/
https://ncbi.nlm.nih.gov/pubmed/23043240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn303030t
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