Telomere Maintenance Mechanisms in Cancer

Tumour cells can adopt telomere maintenance mechanisms (TMMs) to avoid telomere shortening, an inevitable process due to successive cell divisions. In most tumour cells, telomere length (TL) is maintained by reactivation of telomerase, while a small part acquires immortality through the telomerase-i...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Main Authors: Bordeira Gaspar, Tiago, Sá, Ana, Lopes, José Manuel, Sobrinho-Simões, Manuel, Soares, Paula, Vinagre, João
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977181/
https://ncbi.nlm.nih.gov/pubmed/29751586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9050241
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