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Telomere Maintenance Mechanisms in Cancer: Clinical Implications

The presence of immortal cell populations with an up-regulated telomere maintenance mechanism (TMM) is an almost univer-sal characteristic of cancers, whereas normal somatic cells are unable to prevent proliferation-associated telomere shortening and have a limited proliferative potential. TMMs and...

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Détails bibliographiques
Publié dans:Curr Pharm Des
Auteur principal: Reddel, Roger R
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262939/
https://ncbi.nlm.nih.gov/pubmed/24975603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1381612820666140630101047
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