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Telomere Maintenance Mechanisms in Cancer

Tumour cells can adopt telomere maintenance mechanisms (TMMs) to avoid telomere shortening, an inevitable process due to successive cell divisions. In most tumour cells, telomere length (TL) is maintained by reactivation of telomerase, while a small part acquires immortality through the telomerase-i...

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Foilsithe in:Genes (Basel)
Main Authors: Bordeira Gaspar, Tiago, Sá, Ana, Lopes, José Manuel, Sobrinho-Simões, Manuel, Soares, Paula, Vinagre, João
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977181/
https://ncbi.nlm.nih.gov/pubmed/29751586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9050241
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