Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes

Approximately 10% to 15% of human cancers lack detectable telomerase activity, and a subset of these maintain telomere lengths by the telomerase-independent telomere maintenance mechanism termed alternative lengthening of telomeres (ALT). The ALT phenotype, relatively common in subtypes of sarcomas...

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Main Authors: Heaphy, Christopher M., Subhawong, Andrea P., Hong, Seung-Mo, Goggins, Michael G., Montgomery, Elizabeth A., Gabrielson, Edward, Netto, George J., Epstein, Jonathan I., Lotan, Tamara L., Westra, William H., Shih, Ie-Ming, Iacobuzio-Donahue, Christine A., Maitra, Anirban, Li, Qing K., Eberhart, Charles G., Taube, Janis M., Rakheja, Dinesh, Kurman, Robert J., Wu, T.C., Roden, Richard B., Argani, Pedram, De Marzo, Angelo M., Terracciano, Luigi, Torbenson, Michael, Meeker, Alan K.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Investigative Pathology 2011
נושאים:
Short Communication
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181356/
https://ncbi.nlm.nih.gov/pubmed/21888887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.06.018
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