Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes

Approximately 10% to 15% of human cancers lack detectable telomerase activity, and a subset of these maintain telomere lengths by the telomerase-independent telomere maintenance mechanism termed alternative lengthening of telomeres (ALT). The ALT phenotype, relatively common in subtypes of sarcomas...

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Main Authors: Heaphy, Christopher M., Subhawong, Andrea P., Hong, Seung-Mo, Goggins, Michael G., Montgomery, Elizabeth A., Gabrielson, Edward, Netto, George J., Epstein, Jonathan I., Lotan, Tamara L., Westra, William H., Shih, Ie-Ming, Iacobuzio-Donahue, Christine A., Maitra, Anirban, Li, Qing K., Eberhart, Charles G., Taube, Janis M., Rakheja, Dinesh, Kurman, Robert J., Wu, T.C., Roden, Richard B., Argani, Pedram, De Marzo, Angelo M., Terracciano, Luigi, Torbenson, Michael, Meeker, Alan K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181356/
https://ncbi.nlm.nih.gov/pubmed/21888887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.06.018
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