Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes

Approximately 10% to 15% of human cancers lack detectable telomerase activity, and a subset of these maintain telomere lengths by the telomerase-independent telomere maintenance mechanism termed alternative lengthening of telomeres (ALT). The ALT phenotype, relatively common in subtypes of sarcomas...

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Autors principals: Heaphy, Christopher M., Subhawong, Andrea P., Hong, Seung-Mo, Goggins, Michael G., Montgomery, Elizabeth A., Gabrielson, Edward, Netto, George J., Epstein, Jonathan I., Lotan, Tamara L., Westra, William H., Shih, Ie-Ming, Iacobuzio-Donahue, Christine A., Maitra, Anirban, Li, Qing K., Eberhart, Charles G., Taube, Janis M., Rakheja, Dinesh, Kurman, Robert J., Wu, T.C., Roden, Richard B., Argani, Pedram, De Marzo, Angelo M., Terracciano, Luigi, Torbenson, Michael, Meeker, Alan K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181356/
https://ncbi.nlm.nih.gov/pubmed/21888887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.06.018
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