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Shorter telomeres in luminal B, HER-2 and triple-negative breast cancer subtypes

Telomeres are nucleoprotein structures that protect chromosome ends from degradation and recombination. Cancers often have critically shortened telomeres, contributing to genomic instability. Many of these tumors activate telomerase to stabilize telomeric ends and achieve a capacity for unlimited re...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Heaphy, Christopher M, Subhawong, Andrea Proctor, Gross, Amy L, Konishi, Yuko, Kouprina, Nina, Argani, Pedram, Visvanathan, Kala, Meeker, Alan K
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416483/
https://ncbi.nlm.nih.gov/pubmed/21057458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.198
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