How to Treat a Signal? Current Basis for RET-Genotype-Oriented Choice of Kinase Inhibitors for the Treatment of Medullary Thyroid Cancer

The significance of RET in thyroid cancer comes from solid evidence that, when inherited, an RET activating mutation primes C-cells to transform into medullary carcinomas. Moreover, environmental exposure to radiation also induces rearranged transforming RET “isoforms” that are found in papillary th...

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מידע ביבליוגרפי
Main Authors: Prazeres, Hugo, Torres, Joana, Rodrigues, Fernando, Couto, Joana P., Vinagre, João, Sobrinho-Simões, Manuel, Soares, Paula
פורמט: Artigo
שפה:Inglês
יצא לאור: SAGE-Hindawi Access to Research 2011
נושאים:
Review Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134398/
https://ncbi.nlm.nih.gov/pubmed/21765992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/678357
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