Molecular Basis of Medullary Thyroid Carcinoma: The Role of RET Polymorphisms

Medullary thyroid carcinoma is a rare malignant tumor originating in parafollicular C cells. It accounts for 5 to 8% of all thyroid cancers. MTC develops in either sporadic (75%) or hereditary form (25%). Genetic and molecular studies have demonstrated the involvement of the RET proto-oncogene in he...

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Bibliographic Details
Main Authors: Ceolin, Lucieli, Siqueira, Débora R., Romitti, Mírian, Ferreira, Carla V., Maia, Ana Luiza
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2011
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269683/
https://ncbi.nlm.nih.gov/pubmed/22312249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13010221
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