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Engineered membrane protein antigens successfully induce antibodies against extracellular regions of claudin-5

The production of antibodies against the extracellular regions (ECR) of multispanning membrane proteins is notoriously difficult because of the low productivity and immunogenicity of membrane proteins due to their complex structure and highly conserved sequences among species. Here, we introduce a n...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Hashimoto, Yosuke, Zhou, Wei, Hamauchi, Kohtaroh, Shirakura, Keisuke, Doi, Takefumi, Yagi, Kiyohito, Sawasaki, Tatsuya, Okada, Yoshiaki, Kondoh, Masuo, Takeda, Hiroyuki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976803/
https://ncbi.nlm.nih.gov/pubmed/29849184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26560-9
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