Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing

Granzyme B (GzmB) is a serine protease that has long been thought to function exclusively in lymphocyte-mediated apoptosis. In recent years, this paradigm has been revisited due to the recognition that GzmB accumulates in the extracellular milieu in many autoimmune and chronic inflammatory disorders...

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書誌詳細
出版年:Exp Mol Med
主要な著者: Shen, Yue, Zeglinski, Matthew R., Turner, Christopher T., Raithatha, Sheetal A., Wu, Zhenguo, Russo, Valerio, Oram, Cameron, Hiroyasu, Sho, Nabai, Layla, Zhao, Hongyan, Bozin, Tatjana, Westendorf, Kathryn, Kopko, Irina, Huang, Rachel, Arns, Steve, Tan, Jason, Zeng, Haishan, Boey, Anthony, Liggins, Richard, Jaquith, James, Cameron, Dale R., Papp, Anthony, Granville, David J.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976625/
https://ncbi.nlm.nih.gov/pubmed/29849046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0095-0
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