Targeting Gpr52 lowers mutant HTT levels and rescues Huntington’s disease-associated phenotypes

See Huang and Gitler (doi:10.1093/brain/awy112) for a scientific commentary on this article. Lowering the levels of disease-causing proteins is an attractive treatment strategy for neurodegenerative disorders, among which Huntington’s disease is an appealing disease for testing this strategy because...

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Vydáno v:Brain
Hlavní autoři: Song, Haikun, Li, Hexuan, Guo, Shimeng, Pan, Yuyin, Fu, Yuhua, Zhou, Zijian, Li, Zhaoyang, Wen, Xue, Sun, Xiaoli, He, Bingqing, Gu, Haifeng, Zhao, Quan, Wang, Cen, An, Ping, Luo, Shouqing, Hu, Youhong, Xie, Xin, Lu, Boxun
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972579/
https://ncbi.nlm.nih.gov/pubmed/29608652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy081
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