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HIPK3 modulates autophagy and HTT protein levels in neuronal and mouse models of Huntington disease
Macroautophagy/autophagy is an important cellular protein quality control process that clears intracellular aggregate-prone proteins. These proteins may cause neurodegenerative disorders such as Huntington disease (HD), which is mainly caused by the cytotoxicity of the mutant HTT/Hdh protein (mHTT)....
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| Publicado no: | Autophagy |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846548/ https://ncbi.nlm.nih.gov/pubmed/29130397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1393130 |
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