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Early alterations of autophagy in Huntington disease-like mice
In a recent study, we reported in vivo evidence of early and sustained alterations of autophagy markers in a novel knock-in mouse model of Huntington disease (HD). The novel model is derived from selective breeding of HdhQ150 knock-in mice to generate mice with ∼200 CAG/polyglutamine repeats (HdhQ20...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039724/ https://ncbi.nlm.nih.gov/pubmed/20935460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.8.13617 |
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