Early autophagic response in a novel knock-in model of Huntington disease

The aggregation of mutant polyglutamine (polyQ) proteins has sparked interest in the role of protein quality-control pathways in Huntington's disease (HD) and related polyQ disorders. Employing a novel knock-in HD mouse model, we provide in vivo evidence of early, sustained alterations of autop...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Heng, Mary Y., Duong, Duy K., Albin, Roger L., Tallaksen-Greene, Sara J., Hunter, Jesse M., Lesort, Mathieu J., Osmand, Alex, Paulson, Henry L., Detloff, Peter J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2010
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935855/
https://ncbi.nlm.nih.gov/pubmed/20616151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq285
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller