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Allelic series of Huntington's disease knock-in mice reveals expression discorrelates

Identifying molecular drivers of pathology provides potential therapeutic targets. Differentiating between drivers and coincidental molecular alterations presents a major challenge. Variation unrelated to pathology further complicates transcriptomic, proteomic and metabolomic studies which measure l...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Mol Genet
Egile Nagusiak: Kumar, Ashish, Zhang, Jennifer, Tallaksen-Greene, Sara, Crowley, Michael R., Crossman, David K., Morton, A. Jennifer, Van Groen, Thomas, Kadish, Inga, Albin, Roger L., Lesort, Mathieu, Detloff, Peter J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805312/
https://ncbi.nlm.nih.gov/pubmed/26908599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw040
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