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Altered autophagy in the mice with a deficiency of saposin A and saposin B

Combined saposin A and saposin B deficiency (AB(−/−)) was created in mice by knock-in of point mutations into the saposin A and B domains of the Psap (encoding prosaposin) locus. PSAP is the precursor of saposin A, saposin B and two other members, saposin C and saposin D. Those four saposins have mu...

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Autores principales: Sun, Ying, Grabowski, Gregory A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722325/
https://ncbi.nlm.nih.gov/pubmed/23697974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24919
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