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Tissue-specific effects of saposin A and saposin B on glycosphingolipid degradation in mutant mice
Individual saposin A (A−/−) and saposin B (B−/−)-deficient mice show unique phenotypes caused by insufficient degradation of myelin-related glycosphingolipids (GSLs): galactosylceramide and galactosylsphingosine and sulfatide, respectively. To gain insight into the interrelated functions of saposins...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708521/ https://ncbi.nlm.nih.gov/pubmed/23446636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt096 |
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