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Cathepsin-mediated regulation of autophagy in saposin C deficiency
Saposin C deficiency, a rare variant form of Gaucher disease, is due to mutations in the prosaposin gene (PSAP) affecting saposin C expression and/or function. We previously reported that saposin C mutations affecting one cysteine residue result in autophagy dysfunction. We further demonstrated that...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552889/ https://ncbi.nlm.nih.gov/pubmed/23108186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22557 |
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