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Interaction of saposin D with membranes: effect of anionic phospholipids and sphingolipids.

Saposin (Sap) D is an endolysosomal protein that, together with three other similar proteins, Sap A, Sap B and Sap C, is involved in the degradation of sphingolipids and, possibly, in the solubilization and transport of gangliosides. We found that Sap D is able to destabilize and disrupt membranes c...

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Autori principali: Ciaffoni, Fiorella, Tatti, Massimo, Salvioli, Rosa, Vaccaro, Anna Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223540/
https://ncbi.nlm.nih.gov/pubmed/12733985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030359
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