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Preparation of Human Nuclear RNA m(6)A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity
N(6)-Methyladenosine (m(6)A) represents the most prevalent internal modification in messenger and long noncoding RNAs. There has been a surge of interest toward understanding the biological significance of m(6)A modification. In this chapter, we describe the methods for biochemically studying the re...
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Publicado no: | Methods Enzymol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5971108/ https://ncbi.nlm.nih.gov/pubmed/26253968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.03.013 |
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