Detailed resume of RNA m6A demethylases

N6-Methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA, playing critical role in various bioprocesses. Like other epigenetic modifications, m6A modification can be catalyzed by the methyltransferase complex and erased dynamically to maintain cells homeostasis. Up to n...

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Detalhes bibliográficos
Main Authors: Dandan Shen, Bo Wang, Ya Gao, Lijuan Zhao, Yaping Bi, Jinge Zhang, Ning Wang, Huiqin Kang, Jingru Pang, Ying Liu, Luping Pang, Zhe-Sheng Chen, Yi-Chao Zheng, Hong-Min Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-05-01
Colecção:Acta Pharmaceutica Sinica B
Assuntos:
FTO
ALKBH5
RNA demethylation
Diseases
Inhibitors
Screening
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211383522000168
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