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Antimicrobial Activity, AME Resistance, and A-Site Binding Studies of Anthraquinone–Neomycin Conjugates
The antibacterial effects of aminoglycosides are based on their association with the A-site of bacterial rRNA and interference with the translational process in the bacterial cell, causing cell death. The clinical use of aminoglycosides is complicated by resistance and side effects, some of which ar...
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| Udgivet i: | ACS Infect Dis |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5971063/ https://ncbi.nlm.nih.gov/pubmed/28103015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00176 |
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