Lataa...

Synthesis of C‐14 labeled GABA(A) α2/α3 selective partial agonists and the investigation of late‐occurring and long‐circulating metabolites of GABA(A) receptor modulator AZD7325

Anxiolytic activity has been associated with GABA(A) α2 and α3 subunits. Several target compounds were identified and required in C‐14 labeled form to enable a better understanding of their drug metabolism and pharmacokinetic properties. AZD7325 is a selective GABA(A) α2 and α3 receptor modulator in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Labelled Comp Radiopharm
Päätekijät: Artelsmair, Markus, Gu, Chungang, Lewis, Richard J., Elmore, Charles S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969218/
https://ncbi.nlm.nih.gov/pubmed/29314165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3602
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!