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Radical transfer in E. coli ribonucleotide reductase: a NH(2)Y(731)/R(411)A-α mutant unmasks a new conformation of the pathway residue 731
Ribonucleotide reductases (RNRs) catalyze the conversion of ribonucleotides to deoxyribonucleotides in all living organisms. The catalytic cycle of E. coli RNR involves a long-range proton-coupled electron transfer (PCET) from a tyrosyl radical (Y(122)˙) in subunit β2 to a cysteine (C(439)) in the a...
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| Yayımlandı: | Chem Sci |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Royal Society of Chemistry
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5968753/ https://ncbi.nlm.nih.gov/pubmed/29899944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03460d |
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