Hydrogen Bond Network between Amino Acid Radical Intermediates on the Proton-Coupled Electron Transfer Pathway of E. coli α2 Ribonucleotide Reductase

[Image: see text] Ribonucleotide reductases (RNRs) catalyze the conversion of ribonucleotides to deoxyribonucleotides in all organisms. In all Class Ia RNRs, initiation of nucleotide diphosphate (NDP) reduction requires a reversible oxidation over 35 Å by a tyrosyl radical (Y(122)•, Escherichia coli...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Nick, Thomas U., Lee, Wankyu, Koßmann, Simone, Neese, Frank, Stubbe, JoAnne, Bennati, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304443/
https://ncbi.nlm.nih.gov/pubmed/25516424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja510513z
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