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Redox-Linked Changes to the Hydrogen Bonding Network of Ribonucleotide Reductase β2

Ribonucleotide reductase (RNR) catalyzes the conversion of nucleoside diphosphates (NDPs) to 2′-deoxynucleotides, a critical step in DNA replication and repair in all organisms. The class Ia RNRs, which are found in aerobic bacteria and all eukaryotes, are a complex of two subunits: α2 and β2. β2 co...

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Detalhes bibliográficos
Main Authors: Offenbacher, Adam R., Minnihan, Ellen C., Stubbe, JoAnne, Barry, Bridgette A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694779/
https://ncbi.nlm.nih.gov/pubmed/23594029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3032949
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