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Redox-Linked Conformational Control of Proton Coupled Electron Transfer: Y122 in the Ribonucleotide Reductase β2 Subunit

Tyrosyl radicals play essential roles in biological proton coupled electron transfer (PCET) reactions. Ribonucleotide reductase (RNR) catalyzes the reduction of ribonucleotides and is vital in DNA replication in all organisms. Class Ia RNRs consist of α2 and β2 homodimeric subunits. In class 1a RNR,...

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Detalhes bibliográficos
Main Authors: Offenbacher, Adam R., Burns, Lori A., Sherrill, C. David, Barry, Bridgette A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757525/
https://ncbi.nlm.nih.gov/pubmed/23822111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp404757r
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