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Integrating rare genetic variants into pharmacogenetic drug response predictions
BACKGROUND: Variability in genes implicated in drug pharmacokinetics or drug response can modulate treatment efficacy or predispose to adverse drug reactions. Besides common genetic polymorphisms, recent sequencing projects revealed a plethora of rare genetic variants in genes encoding proteins invo...
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| Publicado no: | Hum Genomics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5968569/ https://ncbi.nlm.nih.gov/pubmed/29793534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-018-0157-3 |
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