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Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data

Up to half of all patients do not respond to pharmacological treatment as intended. A substantial fraction of these inter-individual differences is due to heritable factors and a growing number of associations between genetic variations and drug response phenotypes have been identified. Importantly,...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhou, Yitian, Fujikura, Kohei, Mkrtchian, Souren, Lauschke, Volker M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288784/
https://ncbi.nlm.nih.gov/pubmed/30564131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01437
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