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An optimized prediction framework to assess the functional impact of pharmacogenetic variants
Prediction of phenotypic consequences of mutations constitutes an important aspect of precision medicine. Current computational tools mostly rely on evolutionary conservation and have been calibrated on variants associated with disease, which poses conceptual problems for assessment of variants in p...
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| Publicado no: | Pharmacogenomics J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462826/ https://ncbi.nlm.nih.gov/pubmed/30206299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41397-018-0044-2 |
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