טוען...

Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions

High failure rates of drug candidates in the clinics, restricted-use warnings as well as withdrawals of drugs in postmarketing stages are of substantial concern for the pharmaceutical industry and drug-induced liver injury (DILI) constitutes one of the most frequent reasons for such safety failures....

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Toxicol Sci
Main Authors: Vorrink, Sabine U, Zhou, Yitian, Ingelman-Sundberg, Magnus, Lauschke, Volker M
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974779/
https://ncbi.nlm.nih.gov/pubmed/29590495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy058
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