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Cardiac mTORC1 Dysregulation Impacts Stress Adaptation and Survival in Huntington’s Disease
Huntington’s disease (HD) is a dominantly inherited neurological disorder caused by CAG-repeat expansion in exon 1 of Huntingtin (HTT). But in addition to the neurological disease, mutant HTT (mHTT), which is ubiquitously expressed, impairs other organ systems. Indeed, epidemiological and animal mod...
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| Veröffentlicht in: | Cell Rep |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5967646/ https://ncbi.nlm.nih.gov/pubmed/29694882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.117 |
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