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Identification of a rare COCH mutation by whole-exome sequencing: Implications for personalized therapeutic rehabilitation in an Austrian family with non-syndromic autosomal dominant late-onset hearing loss

BACKGROUND: Non-syndromic autosomal dominant hearing impairment is characteristically postlingual in onset. Genetic diagnostics are essential for genetic counselling, disease prognosis and understanding of the molecular mechanisms of disease. To date, 36 causative genes have been identified, many in...

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Publicado no:Wien Klin Wochenschr
Main Authors: Parzefall, Thomas, Frohne, Alexandra, Koenighofer, Martin, Kirchnawy, Andreas, Streubel, Berthold, Schoefer, Christian, Gstoettner, Wolfgang, Frei, Klemens, Lucas, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966484/
https://ncbi.nlm.nih.gov/pubmed/28733840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00508-017-1230-y
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