SRC-3 coactivator governs dynamic estrogen-induced chromatin looping interactions during transcription

Enhancers are thought to activate transcription by physically contacting promoters via looping. However, direct assays demonstrating these contacts are required to mechanistically verify such cellular determinants of enhancer function. Here, we present versatile cell-free assays to further determine...

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Библиографические подробности
Опубликовано в: :Mol Cell
Главные авторы: Panigrahi, Anil K., Foulds, Charles E., Lanz, Rainer B., Hamilton, Ross A., Yi, Ping, Lonard, David M., Tsai, Ming-Jer, Tsai, Sophia Y., O’Malley, Bert W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966282/
https://ncbi.nlm.nih.gov/pubmed/29775582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.014
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