SRC-3 coactivator governs dynamic estrogen-induced chromatin looping interactions during transcription

Enhancers are thought to activate transcription by physically contacting promoters via looping. However, direct assays demonstrating these contacts are required to mechanistically verify such cellular determinants of enhancer function. Here, we present versatile cell-free assays to further determine...

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Udgivet i:Mol Cell
Main Authors: Panigrahi, Anil K., Foulds, Charles E., Lanz, Rainer B., Hamilton, Ross A., Yi, Ping, Lonard, David M., Tsai, Ming-Jer, Tsai, Sophia Y., O’Malley, Bert W.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966282/
https://ncbi.nlm.nih.gov/pubmed/29775582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.014
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