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SRC-3 coactivator governs dynamic estrogen-induced chromatin looping interactions during transcription

Enhancers are thought to activate transcription by physically contacting promoters via looping. However, direct assays demonstrating these contacts are required to mechanistically verify such cellular determinants of enhancer function. Here, we present versatile cell-free assays to further determine...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Panigrahi, Anil K., Foulds, Charles E., Lanz, Rainer B., Hamilton, Ross A., Yi, Ping, Lonard, David M., Tsai, Ming-Jer, Tsai, Sophia Y., O’Malley, Bert W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966282/
https://ncbi.nlm.nih.gov/pubmed/29775582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.014
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