Atypical Protein Kinase C Regulates Dual Pathways for Degradation of the Oncogenic Coactivator SRC-3/AIB1

SRC-3/AIB1 is a steroid receptor coactivator with potent growth promoting activity and its overexpression is sufficient to induce tumorigenesis. Previous studies indicate that the cellular level of SRC-3 is tightly regulated by both ubiquitin-dependent and ubiquitin-independent proteasomal degradati...

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Detalhes bibliográficos
Main Authors: Yi, Ping, Feng, Qin, Amazit, Larbi, Lonard, David M., Tsai, Sophia Y., Tsai, Ming-Jer, O'Malley, Bert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293272/
https://ncbi.nlm.nih.gov/pubmed/18313384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.12.030
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