SRC-3 coactivator governs dynamic estrogen-induced chromatin looping interactions during transcription

Enhancers are thought to activate transcription by physically contacting promoters via looping. However, direct assays demonstrating these contacts are required to mechanistically verify such cellular determinants of enhancer function. Here, we present versatile cell-free assays to further determine...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Panigrahi, Anil K., Foulds, Charles E., Lanz, Rainer B., Hamilton, Ross A., Yi, Ping, Lonard, David M., Tsai, Ming-Jer, Tsai, Sophia Y., O’Malley, Bert W.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966282/
https://ncbi.nlm.nih.gov/pubmed/29775582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.014
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