UniPR1331, a small molecule targeting Eph/ephrin interaction, prolongs survival in glioblastoma and potentiates the effect of antiangiogenic therapy in mice

Glioblastoma multiforme (GBM) is the most malignant brain tumor, showing high resistance to standard therapeutic approaches that combine surgery, radiotherapy, and chemotherapy. As opposed to healthy tissues, EphA2 has been found highly expressed in specimens of glioblastoma, and increased expressio...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Festuccia, Claudio, Gravina, Giovanni Luca, Giorgio, Carmine, Mancini, Andrea, Pellegrini, Cristina, Colapietro, Alessandro, Delle Monache, Simona, Maturo, Maria Giovanna, Sferra, Roberta, Chiodelli, Paola, Rusnati, Marco, Cantoni, Annamaria, Castelli, Riccardo, Vacondio, Federica, Lodola, Alessio, Tognolini, Massimiliano
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2018
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966254/
https://ncbi.nlm.nih.gov/pubmed/29849945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25272
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