UniPR1331, a small molecule targeting Eph/ephrin interaction, prolongs survival in glioblastoma and potentiates the effect of antiangiogenic therapy in mice

Glioblastoma multiforme (GBM) is the most malignant brain tumor, showing high resistance to standard therapeutic approaches that combine surgery, radiotherapy, and chemotherapy. As opposed to healthy tissues, EphA2 has been found highly expressed in specimens of glioblastoma, and increased expressio...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Festuccia, Claudio, Gravina, Giovanni Luca, Giorgio, Carmine, Mancini, Andrea, Pellegrini, Cristina, Colapietro, Alessandro, Delle Monache, Simona, Maturo, Maria Giovanna, Sferra, Roberta, Chiodelli, Paola, Rusnati, Marco, Cantoni, Annamaria, Castelli, Riccardo, Vacondio, Federica, Lodola, Alessio, Tognolini, Massimiliano
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966254/
https://ncbi.nlm.nih.gov/pubmed/29849945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25272
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