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UniPR1331, a small molecule targeting Eph/ephrin interaction, prolongs survival in glioblastoma and potentiates the effect of antiangiogenic therapy in mice

Glioblastoma multiforme (GBM) is the most malignant brain tumor, showing high resistance to standard therapeutic approaches that combine surgery, radiotherapy, and chemotherapy. As opposed to healthy tissues, EphA2 has been found highly expressed in specimens of glioblastoma, and increased expressio...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Festuccia, Claudio, Gravina, Giovanni Luca, Giorgio, Carmine, Mancini, Andrea, Pellegrini, Cristina, Colapietro, Alessandro, Delle Monache, Simona, Maturo, Maria Giovanna, Sferra, Roberta, Chiodelli, Paola, Rusnati, Marco, Cantoni, Annamaria, Castelli, Riccardo, Vacondio, Federica, Lodola, Alessio, Tognolini, Massimiliano
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966254/
https://ncbi.nlm.nih.gov/pubmed/29849945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25272
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