eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures

Alterations in the balance of inhibitory and excitatory synaptic transmission have been implicated in the pathogenesis of neurological disorders such as epilepsy. Eukaryotic elongation factor 2 kinase (eEF2K) is a highly regulated, ubiquitous kinase involved in the control of protein translation. He...

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Vydáno v:Cereb Cortex
Hlavní autoři: Heise, Christopher, Taha, Elham, Murru, Luca, Ponzoni, Luisa, Cattaneo, Angela, Guarnieri, Fabrizia C., Montani, Caterina, Mossa, Adele, Vezzoli, Elena, Ippolito, Giulio, Zapata, Jonathan, Barrera, Iliana, Ryazanov, Alexey G., Cook, James, Poe, Michael, Stephen, Michael Rajesh, Kopanitsa, Maksym, Benfante, Roberta, Rusconi, Francesco, Braida, Daniela, Francolini, Maura, Proud, Christopher G., Valtorta, Flavia, Passafaro, Maria, Sala, Mariaelvina, Bachi, Angela, Verpelli, Chiara, Rosenblum, Kobi, Sala, Carlo
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963824/
https://ncbi.nlm.nih.gov/pubmed/27005990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhw075
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