Ribosomal stress activates eEF2K–eEF2 pathway causing translation elongation inhibition and recruitment of Terminal Oligopyrimidine (TOP) mRNAs on polysomes

The synthesis of adequate amounts of ribosomes is an essential task for the cell. It is therefore not surprising that regulatory circuits exist to organize the synthesis of ribosomal components. It has been shown that defect in ribosome biogenesis (ribosomal stress) induces apoptosis or cell cycle a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Gismondi, Angelo, Caldarola, Sara, Lisi, Gaia, Juli, Giada, Chellini, Lidia, Iadevaia, Valentina, Proud, Christopher G., Loreni, Fabrizio
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
Molecular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227798/
https://ncbi.nlm.nih.gov/pubmed/25332393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku996
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares