eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures

Alterations in the balance of inhibitory and excitatory synaptic transmission have been implicated in the pathogenesis of neurological disorders such as epilepsy. Eukaryotic elongation factor 2 kinase (eEF2K) is a highly regulated, ubiquitous kinase involved in the control of protein translation. He...

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Pubblicato in:Cereb Cortex
Autori principali: Heise, Christopher, Taha, Elham, Murru, Luca, Ponzoni, Luisa, Cattaneo, Angela, Guarnieri, Fabrizia C., Montani, Caterina, Mossa, Adele, Vezzoli, Elena, Ippolito, Giulio, Zapata, Jonathan, Barrera, Iliana, Ryazanov, Alexey G., Cook, James, Poe, Michael, Stephen, Michael Rajesh, Kopanitsa, Maksym, Benfante, Roberta, Rusconi, Francesco, Braida, Daniela, Francolini, Maura, Proud, Christopher G., Valtorta, Flavia, Passafaro, Maria, Sala, Mariaelvina, Bachi, Angela, Verpelli, Chiara, Rosenblum, Kobi, Sala, Carlo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963824/
https://ncbi.nlm.nih.gov/pubmed/27005990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhw075
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