Synaptic Activity Controls Dendritic Spine Morphology by Modulating eEF2-Dependent BDNF Synthesis

Activity-dependent changes in synaptic structure and spine morphology are required for learning and memory, and depend on protein translation. We show that the kinase for eukaryotic elongation factor 2 (eEF2K) regulates dendritic spine stability and synaptic structure by modulating activity-dependen...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Verpelli, Chiara, Piccoli, Giovanni, Zibetti, Cristina, Zanchi, Alice, Gardoni, Fabrizio, Huang, Kun, Brambilla, Dario, Di Luca, Monica, Battaglioli, Elena, Sala, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632604/
https://ncbi.nlm.nih.gov/pubmed/20427644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0119-10.2010
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